Association between cumulus cells—mRNA levels of AMHR2 and FSHR with oocyte maturity

Abstract Background The gene expression of anti-Mullerian hormone receptor type 2 ( AMHR2 ) and follicle stimulating (FSHR) in cumulus cells (CCs) isolated from mature immature oocytes was studied as a possible non-invasive approach for determining oocyte maturity quality. CCs 100 infertile women with different etiologic factors were subdivided into control (CCs MII) case GV) group. Q-PCR used to evaluate FSHR mRNA levels oocytes. Results genes are significantly overexpressed (4–6 fold) relative oocyte. level terms subgroups is P value 0.000). show no significant difference regarding 0.575). Conclusion It seems that the could help understanding molecular mechanism maturation process.